Regulation of glutaminolysis via the NF-kB-PKCe axis in lung cancer cells
Hanna Borlinghaus, Falk Schreiber, Maria Heredia Chavez (annotation)
Glutaminase C (GAC) catalyses the conversion of glutamine to glutamate. Glutamate then enters the tricarboxylic cycle. High availability of glutamate is important for tumor cells to satisfy their increased need for energy and synthesis of macromolecules.
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